How to Safely Self Inject a B12 Shot Perfect for IV Med Spa Clients! , Steps to give yourself an intramuscular shot:, 1 Prep Your Supplies: If youre drawing up B12 yourself, attach a needle to vitamininjections Offer this weekend only Vitamin injections are treatments where essential vitamins are delivered directly into the body via an injectionusually into muscle (intramuscular) or just under the skin. They're popular in B12 Shots at Home: How, Where & How Often to Inject Yourself AZ IV Medics Painless Self Injection 1.3 M Views! YouTube