Clinical guidelines for the recognition of melanoma of the foot and nail unit Journal of Foot and Ankle Research Springer Nature Link Frontiers Neural and Endocrinal Pathobiochemistry of Vitiligo: Comparative Study for a Hypothesized Mechanism Pediatric and Adolescent Nail Disorders Actas Dermo Sifiliogrficas Causes and treatments of herpetic whitlow The major cause of whitlow is herpes simplex virus. The skin around the fingernail is mostly affected. Its early signs include severe pain around the fingers.