BPC 157: What It Is, What We Know, and Why Its Use for Arthritis Remains Unproven San Diego Orthobiologics Medical Group The Basics Behind BPC 157 Injections and Their Effectiveness Your Health Magazine Frontiers Pharmacokinetics, distribution, metabolism, and excretion of body protective compound 157, a potential drug for treating various wounds, in rats and dogs People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation.